Extraction disk is a solid phase extraction (SPE) consumable with high specific surface area and high-density adsorbent membrane as the core, designed for fast, efficient, and low solvent consumption pretreatment, suitable for enrichment and purification of trace target substances in complex samples such as environment, food, biology, and pharmaceuticals. The elution volume is 0.5-2 mL, which can be directly injected into LC-MS/MS without nitrogen blowing concentration. Easy to use, compatible with ordinary microporous filtration devices, and can also be installed in 96 well plates and online SPE systems. Environmentally friendly, reducing organic solvents by over 70%, in line with the concept of green laboratory.